安世恒,男,1976年生,河南省临颍人,博士,教授,博士生导师,河南省特聘教授。1998年毕业于必赢线路检测中心植物保护专业;2002年毕业于必赢线路检测中心农业昆虫与害虫防治专业,获硕士学位;2005年毕业于浙江大学,获博士学位。中国昆虫学会理事,中国昆虫学会发育与遗传分会委员,中国昆虫学会青年工作委员会委员。河南省教育厅学术技术带头人,河南省优秀青年科技专家,河南省特聘教授。兼任河南省昆虫学会副理事长。
主要从事昆虫生理生化与分子生物学的研究,主讲“普通昆虫学”、“昆虫学研究进展”等本科生和研究生课程,获国家级精品课程及国家双语教学示范课程。编写专著3部。曾获河南省五四青年奖章,河南省青少年科技创新奖及河南省青年科技奖等。
一、获得学术奖励
1、控害生物基因的功能研究与开发利用. 2014年河南省科技进步三等奖. 第二完成人
2、果品采后害虫热控技术研究与应用. 2014年河南省科学技术成果. 第二完成人
二、承担及完成的主要科研项目
1、国家自然科学基金面上项目:MAPK/ERK信号通路参与PBAN调控家蚕性信息素生物
合成分子机制的解析,31970472,57万元,2020.01 - 2023.12,主持
2、国家自然基金面上项目:PBAN调控棉铃虫糖转运蛋白参与性信息素合成的分子机制解析,31772536,2018.1-2021.12,主持
3、 国家自然基金面上项目:钙调磷酸酶调控棉铃虫性信息素合成分子机制的研究,31472041,2015.1-2018.12,主持
4、 国家自然基金面上项目:鞣化激素对棉铃虫幼虫脂肪体基因表达调控机理及其生理功能,31172156,2012.1-2015.12,主持
5、河南省高校科技创新人才支持计划: PBAN调控棉铃虫性信息素合成相关蛋白的鉴定及其功能分析,15HASTIT027,2015.1-2017.12,主持人
三、发表的主要论文
1. Zhao W, Wang K, Chang Y, Zhang B, Li F, Meng Y, Li M, Zhao Q*, An S*(通讯作者)(2022) OsHyPRP06/R3L1 regulates root system development and salt tolerance via apoplastic ROS homeostasis in rice (Oryza sativa L.). Plant Cell Environ. 45(3):900-914. doi: 10.1111/pce.14180.
2. Wei J, Yao X, Yang S, Liu S, Zhou S, Cen J, Liu X, Du M*, Tang Q, An S*(通讯作者)(2021)Suppression of Calcineurin Enhances the Toxicity of Cry1Ac to Helicoverpa armigera. Front Microbiol. 12(2):634619. doi: 10.3389/fmicb.
3. Wei J, Yang S, Zhou S, Liu S, Cao P, Liu X, Du M*, An S*(通讯作者)(2021)Suppressing calcineurin activity increasesthe toxicity of Cry2Ab to Helicoverpa armigera. Pest Manag Sci. 77(4):2142-2150.
4. Yao S, Yang Y, Xue Y, Zhao W, Liu X, Du M, Yin X, Guan R*, Wei J*, An S*(通讯作者)(2021) New insights on the effects of spinosad on the development of Helicoverpa armigera. Ecotoxicol Environ Saf. 221:112452. doi: 10.1016/j.ecoenv.
5. Yao S, Zhou S, Li X, Liu X, Zhao W, Wei J*, Du M, An S*(通讯作者)(2021) Transcriptome Analysis of Ostrinia furnacalis Female Pheromone Gland: Esters Biosynthesis and Requirement for Mating Success. Front Endocrinol (Lausanne). 12:736906. doi: 10.3389/fendo.
6. Yao S, Zhang Y, Chang Y, Li X, Zhao W*, An S*(通讯作者)(2021). Pyruvate Kinase Is Required for Sex Pheromone Biosynthesis in Helicoverpa armigera. Front Physiol. 12:707389. doi: 10.3389/fphys.
7. Guan R, Li H, Zhang H, An S*(通讯作者)(2020)Comparative analysis of dsRNA-induced lncRNAs in three kinds of insect species. Arch Insect Biochem Physiol. 103(1):e21640. doi: 10.1002/arch.
8. An S(2019). Insect pest control using biotechnology-preface. Arch Insect Biochem Physiol. 102(3):e21624. doi: 10.1002/arch.
9. Wei J, Zhang Y, An S*(通讯作者)(2019)The progress in insect cross-resistance among Bacillus thuringiensis toxins. Arch Insect Biochem Physiol. 102(3):e21547. doi: 10.1002/arch.21547
10. Wei J, Zhang L, Yang S, Xie B, An S*(通讯作者), Liang G*(2018) Assessment of the lethal and sublethal effects by spinetoram on cotton bollworm. PLoS One. 13(9):e0204154. doi: 10.1371/journal.
11. Zhang S, An S, Hoover K, Li Z, Li X, Liu X, Shen Z, Fang H, Ros VID, Zhang Q, Liu X*(2018)Host miRNAs are involved in hormonal regulation of HaSNPV-triggered climbing behaviour in Helicoverpa armigera. Mol Ecol. 27(2):459-475. doi: 10.1111/mec.14457.
12. Wei J, Yang S, Chen L, Liu X, Du M, An S*(通讯作者), Liang G*(2018)Transcriptomic Responses to Different Cry1Ac Selection Stresses in Helicoverpa armigera. Front Physiol. 9:1653. doi: 10.3389/fphys.
13. Zhang Y, Ma N, Yin L, Wei J, Xi Y, Zhao X, Du M, and An S *(通讯作者) (2018) Molecular identification of Sterol Regulatory Element-binding Protein-1c from Helicoverpa armigera pheromone gland. Archives of Insect Biochemistry and Physiology. DOI: 10.1002/arch.21505
14. Zhao W, Li L, Zhang Y, Liu X, Wei J, Xie Y, Du M*, An S*(通讯作者) (2018) Calcineurin is required for male sex pheromone biosynthesis and female acceptance. Insect Mol Biol. 27(3):373-382. (SCI, IF 2.4)
15. Li B, Hou L, Zhu D, Xu X, An S*, Wang X*(2018)Identification and caste-dependent expression patterns of DNA methylation associated genes in Bombus terrestris.Sci Rep. 8(1):2332. (SCI, IF 4.1)
16. Du M, Liu X, Ma N, Liu X, Wei J, Yin X, Zhou S, Rafaeli A, Song Q, An S*(通讯作者) (2017) Calcineurin-mediated Dephosphorylation of Acetyl-coA Carboxylase is Required for Pheromone Biosynthesis Activating Neuropeptide (PBAN)-induced Sex Pheromone Biosynthesis in Helicoverpa armigera. Mol Cell Proteomics. 16(12):2138-2152. (SCI, IF 6.54)
17. Du M, Zhao W, Jurenka R, Liu X, Yin X, Song Q, An S *(通讯作者)(2017) Transcriptome analysis of Helicoverpa armigera male hairpencils: Alcohol biosynthesis and requirement for mating success. Insect Biochem Mol Biol. 87:154-164(SCI, IF 3.78).
18. Song N, An S, Yin X, Cai W, Li H (2016). Application of RNA-seq for mitogenome reconstruction, and reconsideration of long-branch artifacts in Hemiptera phylogeny. Sci Rep. 6:33465. doi: 10.1038/srep33465.
19. Zhang S, An S, Li Z, Wu F, Yang Q, Liu Y, Cao J, Zhang H, Zhang Q, Liu X. (2015)Identification and validation of reference genes for normalization of gene expression analysis using qRT-PCR in Helicoverpa armigera (Lepidoptera: Noctuidae). Gene. 555(2):393-402.
20. Liu X , Sun C, Liu X, Yin X, Wang B, Du M* and An S*(通讯作者) (2015) Multicopper oxidase-1 is required for iron homeostasis in Malpighian tubules of Helicoverpa armigera. Scientific Reports 5, 14784(SCI, IF 5.78)
21. Du M, liu X, Liu X, Yin X, Han S, Song Q, and An S* (2015) Glycerol-3-phosphate O-acyltransferase is required for PBAN-induced sex pheromone biosynthesis in Bombyx mori. Scientific Reports 5, 8110(SCI, IF 5.78)
22. Zhang S, Liu X, Zhu B, Yin X, Du M, Song Q, An S *(2014) Identification of Differentially Expressed Genes in the Pheromone Glands of Mated and Virgin Bombyx mori by Digital Gene Expression Profiling. PLoS ONE 9(10): e111003,(SCI, IF 3.53)
23. Zhang S, Li X, Zhu B, Du M, Yin X and An S* (2014) Molecular identification of a pancreatic lipase-like gene involved in sex pheromone biosynthesis of Bombyx mori. Insect Science 21, 459–468,(SCI, IF 1.78)
24. Du M, Zhang S, Zhu B, Yin X and An S* (2012) Identification of a diacylglycerol acyltransferase 2 gene involved in pheromone biosynthesis activating neuropeptide stimulated pheromone production in Bombyx mori. Journal of Insect Physiology 58: 699–703.(SCI, IF 2.236)
25. Du M, Yin X, Zhang S, Zhu B, Song Q and An S* (2012) Identification of lipases involved in PBAN-stimulated pheromone production in Bombyx mori using the DGE and RNAi approaches. PLoS ONE 7: e31045.(SCI, IF 4.09)
26. An S, Du M, Su L and Yin X (2012) Transcriptional analysis of the sex pheromone biosynthesis signal genes in Bombyx mori. Insect Science 19: 621-632. (SCI, IF 1.12).
27. An S, Dong S, Wang Q, Li S, Gilbert L I, David S, Song Q (2012) Insect Neuropeptide Bursicon Homodimers Induce Innate Immune and Stress Genes during Molting by Activating the NF-kB Transcription Factor Relish. PLoS ONE 7: e34510.(SCI, IF 4.09)
28. An S, Zhang Y, Wang T, luo M, Li C (2012) Molecular characterization of glutaredoxin 2 from Ostrinia furnacalis (Guenée). Integrative Zoology doi: 10.1111/j.1749-4877.2012.00301.x. (SCI, IF 1.2)
29. Stanley DW, Goodman C, An S, Song Q (2012) Prostaglandin A2 influences gene expression in an established insect cell line (BCIRL-HzAM1) cells. Journal of Insect Physiology 58:837-849.(SCI, IF 2.236)
30. An S, Wang S and Song Q (2009) Identification of a novel bursicon-regulated transcriptional regulator, md13379, in the house fly Musca domestica. Archives of Insect Biochemistry and Physiology 70:106-121. (SCI, IF 1.4)
31. Wang S, An S, Stanley D and Song Q (2009) Cloning and characterization of a bursicon-regulated gene Su(H) in the house fly Musca domestica. Insect Science 16:207-217. (SCI, IF 1.1)
32. An S, Wang S, Gilbert L, Beerntsen B, Ellersieck M and Song Q (2008) Global identification of bursicon- regulated genes in Drosophila melanogaster. BMC Genomics 9: 424. (SCI, IF 4.2)
33. Wang S, An S (Co-first author) and Song Q (2008) Transcriptional expression of bursicon and novel bursicon-regulated genes in the house fly Musca domestica. Arch Insect Biochem Physiol 68:100-112. (SCI, IF1.3)
34. Sun Y, An S, Henrich V, Sun X and Song Q (2007) Proteomic identification of PKC-mediated expression of 20E-induced protein in Drosophila melanogaster. Journal of Proteome Research 6:4478 –4488. (SCI, IF 5.6)
35. An S, Shang J, Liu Y, Kumar S, Guo Z, Wang D, Yang Z and Zhang C (2006) Characterization of a unique gene ORF135 from Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus. Virus Genes 32:21–26. (SCI, IF 1.36)
36. An S, Xing L, Shi W and Zhang C (2006) Characterization of Autographa californica multiple nucleopoly-hedrovirus orf17. Acta Virologica 50: 17 – 23. (SCI, IF 0.7)
37. An S, Guo Z and Yin X (2006) Expression and immunocytochemical analysis of Autographa californica nucleopolyhedrovirus (AcMNPV) orf74 gene. Insect Science 13:349-354. (SCI)
38. An S, Wang D, Yang Z, Guo Z, Xu H, Sun J and Zhang C (2005) Characterization of a late expression gene, Open reading frame 128 of Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus. Archives of Virology 150: 2453–2466. (SCI, IF 1.8)
39. An S, Xing L, Kumar S and Zhang C (2005) Analysis of a late gene, orf101 from Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus. Insect Science 12: 335-340.
40. Wang D, An S, Guo Z, Xu H and Zhang C (2005) Characterization of Helicoverpa armigera nucleopolyhedrovirus orf 33 that encodes a novel budded virion derived protein, BV-e31. Archives of Virology 150: 1505–1515. (SCI, IF 1.8)
41. Guo Z, An S, Dun Wang, Liu Y, Kumar S and Zhang C (2005) Characterization of Ha29, a specific gene for Helicoverpa armigera single-nucleocapsid nucleopolyhedrovirus. Journal of Biochemistry and Molecular Biology 38:354-359. (SCI, IF 1.5)